COVID-19 PCR tests are highly sensitive and specific for the virus SARS-CoV-2; the majority of positive results are true positives; there is no evidence that budesonide or HCQ are useful as COVID-19 treatments
Models that predicted COVID-19 would cause 2.2 million deaths in the U.S. were based on the assumption that no measures were taken to prevent the spread of the disease. The reason why the projected figure differed significantly from real-world outcomes is because the assumption in the model didn’t hold true in real life, as measures were taken to reduce the spread of COVID-19. COVID-19 PCR tests are highly specific and sensitive for the virus’ genetic material, and evidence indicates that, by and large, most positive results are true positives. Neither budesonide nor hydroxychloroquine have been approved for treating the disease, as their usefulness has not been proven.