There is no evidence that luciferase is an ingredient in the COVID-19 vaccines
Bioluminescence is a process by which chemical reactions generate light. One such chemical reaction is catalyzed by the enzyme luciferase, which transforms luciferin into light. This process is used in lab research to monitor biological processes, and luciferase was used in the development and evaluation of COVID-19 vaccines. However, luciferase is not an ingredient in any of the COVID-19 vaccines approved or authorized in the U.S.