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Robert Malone made multiple misleading or unsubstantiated claims about COVID-19 and vaccines on The Joe Rogan Experience podcast

The highly contagious Omicron variant has led to record numbers of COVID-19 cases worldwide. Although COVID-19 vaccines are much less effective at preventing infection by this variant compared to previous ones, they remain effective against severe illness and death. Current data indicates that a booster dose enhances this protection. Safety data shows that the benefits of COVID-19 vaccines far outweigh their known and potential risks.

There is no evidence that dietary supplements containing zinc and a zinc ionophore, such as the one promoted by Vladimir Zelenko, are effective against COVID-19

The combination of zinc and a zinc ionophore has been promoted as a way to treat COVID-19, including by family physician Vladimir Zelenko who is selling a dietary supplement called Z-Stack. However, while a 2010 paper found that the combination of zinc and a zinc ionophore can limit coronavirus replication in cells in a lab, there is no evidence that this combination works in humans. Zelenko also claims that vitamin D3 can boost immunity. But while some studies have detected an association between low levels of vitamin D and a higher risk of catching COVID-19 and/or worse COVID-19 outcomes, there is no evidence that taking vitamin D supplements boosts immunity.

COVID-19 vaccines aren’t associated with a higher risk of pregnancy complication, contrary to claim by Daniel Horowitz

While pregnant women were first excluded from clinical trials for COVID-19 vaccines, observational data from many countries now show that COVID-19 vaccines don’t affect pregnancy outcomes. Pregnancy places someone at a higher risk of getting severe COVID-19, and the infection increases the risk of pregnancy complications, including perinatal death. Therefore, COVID-19 vaccination offers benefits to pregnant women.

CDC director’s comments that 75% of COVID-19 deaths are among people with four comorbidities applies only to vaccinated people

COVID-19 vaccines provide a high level of protection against severe disease. The small number of severe cases and deaths among vaccinated adults is dominated by those who have multiple risk factors. These people were at very high risk of severe COVID-19 from the start of the pandemic, and while the vaccines have brought down their risk considerably, they still remain at higher risk than other vaccinated people who don’t have the same risk factors. Unvaccinated people have approximately ten times the risk of hospitalization and death due to COVID-19.

The scientific evidence shows that COVID-19 vaccination reduces the risk of infection and mortality; analysis of cases and deaths from 145 countries is methodologically flawed

Ecological studies compare aggregate data from whole groups or populations and seek correlations between exposure to a potential risk factor and the frequency of disease. They are relatively quick and inexpensive to do compared to studies such as randomized controlled trials. However, there are also important pitfalls to ecological studies. For example, it’s difficult to account for confounding factors in the study, which are variables that affect the outcome of an experiment, but aren’t the variables being studied in the experiment. As such, it is challenging to draw causal inferences solely from an ecological study.

Robert Malone’s statements on The Dana Show about vaccine safety and virus variants are inaccurate and unsupported

All approved and authorized COVID-19 vaccines are very safe and highly effective at preventing severe disease and death. Although some variants might partially evade vaccine protection, booster doses have proven effective at preventing hospitalization and death due to viral variants, including Omicron. No evidence so far indicates that COVID-19 vaccination has played a fundamental role in the evolution of variants that can evade immunity, at least no more than infection.

Contrary to claim in Washington Times op-ed, COVID-19 shots meet the definition of a vaccine

The COVID-19 vaccines safely prompt an immune response that protects individuals from both infection, and to a greater extent, severe COVID-19 disease, even against new variants like Omicron. These are all hallmarks of a vaccine, which means that the COVID-19 vaccines are indeed vaccines. Additionally, the majority of vaccines routinely used, such as the rotavirus and polio vaccines, don’t prevent 100% of infections. In spite of this, these vaccines still effectively reduce the burden of infectious diseases on the world’s population.

Testing in general reveals infections, it doesn’t create them; COVID-19 isn’t the same as the common cold

The COVID-19 pandemic has led to higher than expected deaths in many countries around the world and places a significant burden on healthcare systems. Many hospitals have experienced insufficient capacity in intensive care units, and some have had to cancel surgeries and turn away patients. COVID-19 testing is an invaluable tool that enables us to detect and isolate infected people, thus helping to reduce the spread of the virus.

Contrary to Peter McCullough’s claim, getting vaccinated is safer than getting COVID-19, in spite of rare cases of myocarditis

Although cases of myocarditis have been reported following mRNA vaccination against COVID-19, the cases are rare, usually mild and patients rapidly recover. In contrast, COVID-19 is associated with a higher rate of myocarditis with potential risks of clinical complications. Overall, based on all scientific evidence available, the benefits of vaccines largely outweigh their risks.

Joe Rogan interview with Peter McCullough contains multiple false and unsubstantiated claims about the COVID-19 pandemic and vaccines

To date, more than 241 million people in the U.S. have received at least one dose of COVID-19 vaccine. Clinical trials as well as the safety monitoring of COVID-19 vaccination campaigns provide overwhelming evidence that the vaccines’ benefits far outweigh their risks. There’s no evidence indicating that the amount of spike protein generated by mRNA vaccination is dangerous. The use of multiple doses of COVID-19 vaccines isn’t unusual or unprecedented; some childhood vaccines that have been used for decades also require four or more doses for complete immunization.