Complete vaccine coverage in the U.S. could have prevented almost a quarter of COVID-19 deaths

The COVID-19 vaccines have been shown in clinical trials and real-world data to be highly effective at preventing deaths. Even after all adults became eligible for vaccines, about 40% of Americans remained unvaccinated, falling to 22% by February 2022. These unvaccinated people accounted for the vast majority of deaths in the months that followed. If all these adults had been vaccinated, an estimated 234,000 lives could have been saved by March 2022, representing about a quarter of all COVID-19 deaths up to that point.

Study by German researchers didn’t find significant safety concerns with Pfizer-BioNTech COVID-19 vaccine, contrary to claim by Alex Berenson

The American Academy of Pediatricians recommends that all eligible infants, children, and adolescents six months and older be vaccinated against COVID-19. Although the U.S. Advisory Committee on Immunization Practices (ACIP) voted to add the COVID-19 vaccine to the childhood immunization schedule, this addition doesn’t make the vaccine mandatory for attending schools. Whether a vaccine is mandatory to attend school is up to states.

COVID-19 vaccine boosters reduce the risk of infection and hospitalization; they don’t increase the risk, contrary to claims of vaccines’ “negative efficacy”

Multiple studies show that COVID-19 vaccines protect against severe illness and death. The vaccines also reduce a person’s likelihood of infection, although they are less effective against infection with the more transmissible Omicron subvariants than with previous variants, and this protection wanes over time. Booster doses increase vaccine protection against both infection and severe COVID-19. Yet, Omicron-specific vaccine formulations may be needed to prevent emerging variants from spreading within the population.

Scientific studies show that the Pfizer-BioNTech COVID-19 vaccine reduces transmission; claim by Rob Roos is misleading

COVID-19 vaccines remain highly effective at reducing the risk of severe disease and death. Studies showed that the vaccines are also effective at reducing virus transmission, although this ability has waned in the face of virus variants that emerged later. Most vaccines predating the COVID-19 vaccines—like the pertussis and rotavirus vaccines—don’t prevent transmission but nevertheless produce significant public health benefits, by reducing infection and severe disease in the community. Scientific evidence supports getting vaccinated to protect oneself as well as others.

Analysis by Florida Department of Health about COVID-19 mRNA vaccines contains multiple methodological problems

Much larger studies have found that the benefits of COVID-19 mRNA vaccines continue to outweigh the risks, even in people at the highest risk of post-vaccine myocarditis. The analysis by the Florida Department of Health, used to support the guidance recommending against men aged 18 to 39 getting the COVID-19 mRNA vaccines, is limited in ways that make it unreliable as evidence. The recommendation is based on a comparatively small number of deaths that could produce a statistical fluke and the study design used isn’t suitable for studying death as an adverse event in the first place.

Charlie Kirk’s video listing reasons to oppose COVID-19 vaccines contains multiple incorrect, misleading, and unsupported statements

The U.S. Vaccine Adverse Reporting System (VAERS) serves as a warning system for potential side effects of vaccination. However, VAERS reports contain unverified information and, on their own, can’t demonstrate a causal link between the vaccine and the adverse event. Systematic analyses of safety surveillance data from millions of people show that the COVID-19 vaccines have an excellent safety profile and are highly effective at preventing severe COVID-19 and death.

Biden’s 2021 remarks on the role of COVID-19 vaccines in hurricane preparedness misrepresented in social media posts

Disaster areas are prone to disease outbreaks, due to factors such as crowding in shelters and poor sanitation. COVID-19 vaccines mitigate public health risks associated with disaster areas, as they are highly effective at reducing a person’s risk of severe illness and death from COVID-19. The U.S. Centers for Disease Control and Prevention recommends that people in affected zones stay up to date on their COVID-19 vaccines, to reduce their likelihood of becoming sick with COVID-19 and needing medical care.

Claim that hydroxychloroquine is an effective early treatment for COVID-19 isn’t supported by evidence from clinical trials

The antimalarial hydroxychloroquine (HCQ) was one of the drugs investigated as a potential COVID-19 treatment in the early months of the COVID-19 pandemic. Large clinical trials with thousands of study participants eventually showed it provided no benefit to hospitalized COVID-19 patients. There are no similarly large trials evaluating the effect of early treatment with HCQ, although published results from smaller clinical trials show that HCQ didn’t provide significant benefits for outpatients compared with placebo.

COVID-19 vaccines provide important benefits; SSRN preprint didn’t find COVID-19 vaccines to be “98 times worse” than the virus

COVID-19 vaccines have proven to be highly effective at protecting people from severe disease and death, and they can also reduce one’s chances of developing long COVID. While previous infection confers some degree of protective immunity, infection-induced immunity is unpredictable due to many variables that aren’t within our control, such as disease severity. Vaccination remains the safer and more reliable means of inducing protection against COVID-19.