Search Results for coronavirus

Human DNA does not produce a positive result on the RT-PCR test for SARS-CoV-2

The reverse-transcription PCR (RT-PCR) test is the method of choice for detecting SARS-CoV-2 in samples and is highly specific for the virus. For a PCR test to successfully amplify nucleic acids (DNA or RNA) in a sample, it is necessary for a pair of primers, which are short sequences of single-stranded nucleic acids that recognize and bind to a specific region of the genome, to flank the same target sequence. If only one primer in the pair is able to do so, amplification does not take place and the test produces a negative result. Therefore, even when an RT-PCR test for SARS-CoV-2 uses a primer that matches a human gene sequence, the test would not produce a positive result with human DNA alone because the other primer does not match the human gene sequence.

A vaccine against SARS-CoV-2 would be useful even if the survival rate from COVID-19 is high

Due to the high transmissibility of SARS-CoV-2, hundreds of thousands of people have died despite the high survival rate of COVID-19. A vaccine would limit transmissibility and thereby reduce the total number of deaths. Furthermore, by reducing the rate of infection or perhaps simply disease severity, a vaccine could also reduce non-lethal yet potentially permanent conditions, such as damage to the heart, lungs, and other tissues. Finally, a vaccine could slow the propagation of the virus through a population by helping to achieve herd immunity, which protects vulnerable persons such as the elderly and immunocompromised. Vaccines confer a range of important benefits, even for diseases with a high average rate of survival.

People infected with SARS-CoV-2 can transmit the virus to others, even if they do not show symptoms of the disease and are not considered sick

Scientific evidence indicates that about half of SARS-CoV-2 transmission occurs before infected individuals experience any symptoms of COVID-19. Studies show that asymptomatic carriers, who are people that never develop symptoms of COVID-19, carry as much of the SARS-CoV-2 virus as symptomatic patients and can spread the virus if they do not take adequate measures, such as wearing masks or maintaining physical distance from others.

Listicle of “facts” about COVID-19 contains numerous inaccurate and misleading claims

In 2020, more deaths have occurred than expected relative to previous years (i.e., excess deaths), even more than the number of excess deaths that occurred during the particularly severe flu season of 2017-2018. Countries like Sweden and Japan that did not implement lockdowns have managed to control the outbreak of COVID-19, but this may be due to unique cultural factors such as the voluntary practice of physical distancing and mask-wearing. Published studies have shown that these measures are effective at significantly reducing virus transmission.

Current COVID-19 mortality rate does not predict the future probability of dying from the disease

The COVID-19 cause-specific mortality rate is the proportion of people who have died from the disease relative to the entire population. It is sometimes used to compare mortality between populations of different sizes. It also represents the likelihood that a randomly selected person in the population who was alive at the start of the pandemic already died of the disease. However, it cannot be used to predict an individual’s likelihood of dying from COVID-19 in the future, given the dynamic nature of the epidemic and that every individual’s risk of contracting and dying from COVID-19 is different.

“Plandemic: Indoctornation” video rehashes debunked claims and conspiracy theories about the COVID-19 pandemic and vaccines

Plandemic is a pseudo-documentary produced by American filmmaker Mikki Willis, whose first instalment was published in May 2020. Featuring an interview with anti-vaccination activist and former scientist Judy Mikovits, the video peddled numerous false claims and conspiracy theories about the COVID-19 pandemic and vaccines (see Health Feedback’s review of that video). It achieved immense virality … Continued

Potential role for T cells in COVID-19 immunity accurately reported in National Geographic article

“The article accurately discusses the recent findings about the presence/relevance of T cell response against COVID-19. Indeed, both arms of adaptive immunity, humoral and cellular, contribute in different ways to the body’s fight against viral infections. What remains to be seen and explored in greater detail is how important the role of antigen-specific T cells is in protecting people from a re-infection or ameliorating the disease symptoms.”

Flawed “study” incorrectly claims that countries adopting hydroxychloroquine as a treatment for COVID-19 experienced reduced mortality rates

Some governments have favored the use of hydroxychloroquine for treating or preventing COVID-19. However, this does not necessarily imply that the people within those countries used the drug more often than did people in countries that restricted hydroxychloroquine use. Therefore, correlating countries’ mortality rates with their stance towards hydroxychloroquine use results in a spurious association that is based on flawed reasoning. In contrast, growing evidence from large randomized clinical trials suggests no beneficial effect of hydroxychloroquine in treating COVID-19 patients.

Sweden’s COVID-19 mortality is higher than in most European countries; no evidence whether or how the absence of lockdown impacted this outcome

An analysis of COVID-19 mortality rates shows that Sweden is one of the worst-performing countries in Europe, although Italy, Spain, and the U.K. have experienced higher rates. Countries like Sweden that did not implement lockdowns show a range of mortality rates, making it difficult to determine whether Sweden’s policies had any impact, either positive or negative in the COVID-19 epidemic outcome.

Vaccines undergo strict safety testing before they are licensed for use in the U.S. and many other countries; no validity to the claim of a 33% “death rate” from COVID-19 vaccine

More than a hundred COVID-19 vaccine candidates are in the midst of testing worldwide. The claim that a COVID-19 vaccine has a 33% “death rate” is false; there is no evidence to support it. The claim is most likely based on a separate false claim that five out of 15 volunteers—among whom were four Ukrainian soldiers—died in a vaccine trial in Ukraine, which was refuted by the Ukrainian military. Despite efforts to accelerate the usual timelines used in vaccine development, COVID-19 vaccines are not being approved by public health authorities until they undergo rigorous testing for safety and effectiveness. A vaccine with a demonstrated 33% “death rate” has not been and would never be approved for use in the U.S. or most other countries.