No scientific evidence for the claim that nattokinase can treat long COVID or “detox” COVID-19 vaccines

Nattokinase is an enzyme that was first isolated from natto, a traditional Japanese dish made of fermented soybeans. Research so far has shown that it can break apart proteins involved in blood clotting, which enables it to dissolve blood clots. While one study by Tanikawa et al. found that nattokinase could break down spike protein, the study was unrelated to long COVID and the experiments were performed in cells in the lab. Therefore, the results may not reflect what happens in the human body and also provide no information about its effects on long COVID.

Study led by FDA researchers didn’t find that the Pfizer-BioNTech COVID-19 vaccine caused blood clots, contrary to viral claims on social media

Certain COVID-19 vaccines, specifically the viral vector vaccines like the AstraZeneca and J & J vaccines, are associated with an increased risk of a blood clotting disorder called vaccine-induced thrombotic thrombocytopenia, which can be fatal. At the moment, there isn’t evidence indicating that mRNA COVID-19 vaccines are associated with the same risk. However, it’s important to also consider that getting COVID-19 itself increases a person’s risk of developing blood clotting problems to a greater extent than the viral vector COVID-19 vaccines.

Medical exemptions to COVID-19 vaccines are granted for contraindications, not including history of blood clots or adverse reaction to prior vaccine

COVID-19 vaccines are safe and effective against severe illness and death. People who have contraindications to COVID-19 vaccines can get a medical exemption. However, an adverse reaction to a previous vaccine and a history of blood clots aren’t, on their own, reasons not to vaccinate. On the contrary, COVID-19 vaccines are recommended for people with a history of blood clots, as they are at a higher risk of severe COVID-19 and related complications, including blood clotting.

Comparing SARS-CoV-2 infection rate of vaccinated and unvaccinated populations doesn’t reflect the real COVID-19 vaccine effectiveness

Vaccinated and unvaccinated populations may differ in many characteristics, such as age, population size, social behavior or health seeking behavior. These differences must be taken into consideration when comparing the SARS-CoV-2 infection rates between vaccinated and unvaccinated populations. Failure to do so may lead to biased conclusions. Studies accounting for these differences showed that COVID-19 vaccines effectively reduce the risk of getting sick.

Study in Vietnam showed that Delta infection results in a higher viral load compared to earlier strains, not that vaccinated people are more infectious than unvaccinated people

Multiple studies indicate that Delta variant infection results in a higher viral load compared to infection by the original strain and other variants. However, COVID-19 vaccination remains highly effective at protecting people from illness and hospitalization caused by the Delta variant, which is now the predominant strain in the world. And while the level of protection from infection by vaccines is lower against the Delta variant, vaccinated people still have a lower risk of infection compared to those who are unvaccinated.

The American Journal of Medicine didn’t recommend hydroxychloroquine as a treatment for COVID-19; scientific evidence doesn’t show hydroxychloroquine is effective against COVID-19

No scientific evidence demonstrates that hydroxychloroquine is useful for preventing or treating COVID-19, despite social media posts and articles claiming otherwise. Large, randomized, controlled clinical trials in several countries found that hydroxychloroquine doesn’t produce any benefits in terms of mortality rate or clinical outcomes in COVID-19 patients. Due to the lack of benefits and risk of heart rhythm problems, public health authorities recommend against using hydroxychloroquine to treat COVID-19 patients outside of clinical trials.